Apixaban Drug

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Apixaban Uses, Side Effects & Warnings - Drugs.com

(9 days ago) Warnings. Apixaban increases your risk of severe or fatal bleeding, especially if you take certain medicines at the same time (including some over-the-counter medicines).Tell your doctor about all medicines you have recently used. Call your doctor at once if you have signs of bleeding such as: easy bruising, unusual bleeding, unexpected pain or swelling, feeling very weak or dizzy, …

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Apixaban - FDA prescribing information, side effects and uses

(9 days ago) Unchanged Apixaban is the major drug-related component in human plasma; there are no active circulating metabolites. Elimination. Apixaban is eliminated in both urine and feces. Renal excretion accounts for about 27% of total clearance. Biliary and direct intestinal excretion contributes to elimination of Apixaban in the feces.

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Apixaban - Wikipedia

(8 days ago) Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. [4] [5] [6] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of

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Apixaban Advanced Patient Information - Drugs.com

(Just Now) Apixaban is also used to prevent stroke and blood clots in patients with certain heart rhythm problem (eg, nonvalvular atrial fibrillation). Apixaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps preventing harmful clots from forming in the blood vessels.

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Apixaban (Eliquis) Davis’s Drug Guide

(1 days ago) Reduction in Risk of Stroke/Systemic Embolism in Nonvalvular Atrial Fibrillation. PO (Adults): 5 mg twice daily; Any 2 of the following: age ≥80 yr, weight ≤60 kg, serum creatinine ≥1.5 mg/dL– 2.5 mg twice daily; Concurrent use of strong inhibitors of both CYP3A4 and P-gp– 2.5 mg twice daily; if patient already taking 2.5 mg twice

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apixaban-drug- - UpToDate

(Just Now) A recent retrospective study reported that among 37,000 new users of apixaban or rivaroxaban, apixaban was associated with lower rates of recurrent VTE (hazard ratio [HR] 0.77, 95% CI 0.69-0 …. What's new in family medicine. …patients with MOH were started on a preventive medication and randomized to continue the overused medication or to

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Eliquis (apixaban): Side effects, dosage, uses, and more

(9 days ago) Eliquis is brand-name drug, while warfarin is a generic drug. Brand-name medications usually cost more than generics. A generic version of Eliquis, called apixaban, has been approved.

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Drug interactions with apixaban: A systematic review of the …

(3 days ago) These data suggest that apixaban has significant potential for drugdrug interactions, either with CYP3A/P‐gp modulators or with drugs that may impair hemostasis. The most described adverse drug reactions were adverse drug reactions related to hemorrhage or thrombosis, mostly through pharmacodynamic interactions.

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Apixaban Drug Interaction Potential Anticoagulation Services

(6 days ago) Pharmacodynamic Interactions . The concurrent use of apixaban with other anticoagulants, antiplatelet agents, and nonsteroidal anti-inflammatory agents is expected to increase the risk of bleeding in comparison to use of apixaban alone.. Pharmacokinetic Interactions . 1. The absorption of apixaban is mediated by P-glycoprotein (P-gp).

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Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review

(3 days ago) After an oral dose of apixaban, unchanged apixaban is the major drug-related component in human plasma with no active circulating metabolites present . When a 20-mg radiolabeled dose was administered orally, 56.0% of the dose was recovered in feces and 24.5% was eliminated in urine and unchanged apixaban was the major component in both feces

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Eliquis: Uses, Dosage & Side Effects Information - Drugs.com

(4 days ago) Eliquis is used to lower the risk of stroke or a blood clot in people with a heart rhythm disorder called atrial fibrillation. Eliquis reduces the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery. Eliquis treats blood clots in the veins of your legs ( DVT - deep vein thrombosis) or

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Apixaban: MedlinePlus Drug Information

(Just Now) Apixaban comes as a tablet to take by mouth. It is usually taken with or without food twice a day. When apixaban is taken to prevent DVT and PE after hip or knee replacement surgery, the first dose should be taken at least 12 to 24 hours after surgery. Apixaban is usually taken for 35 days after a hip replacement surgery and for 12 days after

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Apixaban: Side Effects, Dosage, Uses, and More - Healthline

(Just Now) Apixaban oral tablet is a prescription drug used to treat and prevent blood clots such as deep vein thrombosis (DVT) and pulmonary embolism (PE). …

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Apixaban: 7 things you should know - Drugs.com

(8 days ago) Apixaban works by selectively inhibiting (blocking) the effects of factor Xa (FXa), an enzyme that plays a key role in the formation of substances that cause blood clotting. Through its action on FXa, apixaban makes blood less likely to clot. Apixaban belongs to the class of drugs known as factor Xa inhibitors.

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Apixaban Prices, Coupons & Savings Tips - GoodRx

(1 days ago) Apixaban is only available as a generic drug. Prices. Medicare. Drug Info Side Effects. Images. Apixaban is part of the Anticoagulants class and treats Stroke Risk Reduction, Deep Vein Thrombosis, and Pulmonary Embolism.

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Apixaban: Uses, Interactions, Mechanism of Action - DrugBank

(7 days ago) Generic Name Apixaban DrugBank Accession Number DB06605 Background. Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases Label,2.It is marketed under the name Eliquis Label,3.Apixaban

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apixaban oral: Uses, Side Effects, Interactions, Pictures - WebMD

(3 days ago) Drugs & Medications ; Apixaban Tablet ; Apixaban Tablet - Uses, Side Effects, and More Generic Name: apixaban . Apixaban is used to prevent serious blood clots from forming due to a …

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Cost and Eliquis: Financial assistance options, savings, more

(Just Now) Eliquis is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to help prevent or treat certain blood clots in …

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Apixaban C25H25N5O4 - PubChem

(Just Now) Apixaban C25H25N5O4 CID 10182969 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety

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Apixaban (Eliquis): Side Effects, Dosages, Treatment - RxList

(8 days ago) Apixaban is a blood thinner that reduces blood clotting and the risk of stroke. Learn about side effects, drug interactions, dosages, warnings, and more.

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FDA approves first generics of Eliquis FDA

(7 days ago) Apixaban will be dispensed with a Medication Guide for patients that provides instructions on its use and drug safety information. Health care professionals should counsel patients on signs and

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Apixaban - Side Effects, Interactions, Uses, Dosage, Warnings

(5 days ago) Find everything you need to know about Apixaban, including what it is used for, warnings, reviews, side effects, and interactions. Drugs A-Z …

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Critical Analysis of Apixaban Dose Adjustment Criteria - PMC

(3 days ago) The apixaban package labeling advises on the importance of drug interactions, as apixaban is a substrate of both cytochrome P450 3A4 (CYP3A4) and efflux transporter permeability-glycoprotein (P-gp). Co-administration of strong CYP3A4 and P-gp inhibitors or inducers may result in increases or decreases of apixaban exposure,

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Apixaban: a medicine to help prevent blood clots - NHS

(8 days ago) 1. About apixaban. Apixaban is a type of medicine known as an anticoagulant, or blood thinner. It makes your blood flow through your veins more easily. This means your blood will be less likely to make a dangerous blood clot. It's used to treat people who have had a health problem caused by a blood clot, such as:

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CVS Caremark Puts Eliquis Back On Its Formularies

(7 days ago) After objections from patient groups and professional organizations, CVS Caremark has put Eliquis (apixaban) back on its formularies after removing the drug from its lists of covered drugs at the beginning of the year. “This is about decisions between doctors and patients being respected,” said Beth Joyner Waldron, a patient advocate in

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apixaban oral Interactions with Other Medication

(1 days ago) Moderate Interactions. These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. APIXABAN/ASPIRIN (< OR

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Apixaban: Dosage, Mechanism/Onset of Action, Half-Life

(2 days ago) Dosage adjustment of apixaban with concomitant medications: Strong dual CYP3A4 and P-glycoprotein inhibitors (eg, ketoconazole, itraconazole, ritonavir): Recommended apixaban doses >2.5 mg twice daily: Reduce apixaban dose by 50%. Recommended apixaban dose of 2.5 mg twice daily: Avoid concomitant use.

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apixaban (Rx) - Medscape Drugs & Diseases

(9 days ago) Avoid or Use Alternate Drug. Apixaban is also substrate of P-gp; if concomitant administration necessary, adjust and hold dose as clinically necessary; may adjust apixaban dosage according to risk, indication and current dose; for treatment of atrial fibrillation with standard apixaban dose (eg, 5 mg twice daily), reduce apixaban to 2.5 mg

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Apixaban (Oral Route) Description and Brand Names - Mayo Clinic

(9 days ago) Apixaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps preventing harmful clots from forming in the blood vessels. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet. Before Using.

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Eliquis (apixaban) dose, indications, adverse effects - PDR

(9 days ago) The apixaban manufacturer recommends reducing the apixaban dose by 50% when coadministered with drugs that are both strong inhibitors of CYP3A4 and P-gp, such as darunavir. If patients are already receiving 2.5 mg twice daily, avoid …

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CVS Caremark returns Eliquis to formulary after outcry

(7 days ago) The price of Eliquis, also known as apixaban, rose 6% to $529 for a one-month supply in January compared with a year before, according to Patients for Affordable Drugs, an …

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First Generic Alternative to Eliquis® Now Available in Canada

(3 days ago) Apotex Inc., Canada's leading pharmaceutical manufacturer of generic medicines, announced today the launch of APO-ApixabanTM tablets, Canada's first generic alternative to Eliquis®.

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Reference ID: 3237516 - Food and Drug Administration

(5 days ago) ELIQUIS increases the risk of bleeding and can cause serious, potentially fatal, bleeding [see Dosage and Administration (2.2) and Adverse Reactions (6.1)]. Concomitant use of drugs affecting hemostasis increases the risk of bleeding. These include aspirin and other antiplatelet agents, other anticoagulants, heparin, thrombolytic agents, selective

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View Patient And Physician Resources Rx ELIQUIS® (apixaban)

(5 days ago) For patients receiving ELIQUIS doses of 5 mg or 10 mg twice daily, reduce the dose of ELIQUIS by 50% when ELIQUIS is coadministered with drugs that are combined P-gp and strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or ritonavir). In patients already taking 2.5 mg twice daily, avoid coadministration of ELIQUIS with combined P-gp

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Apixaban Drugs BNF NICE

(9 days ago) Drug action Drug action For apixaban. Apixaban is a direct inhibitor of activated factor X (factor Xa). Indications and dose For apixaban Prophylaxis of venous thromboembolism following knee replacement surgery for apixaban By mouth. Adult 2.5 mg twice daily for 10–14 days, to be started 12–24 hours after surgery.

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Paracetamol and Apixaban drug interactions - a phase IV clinical …

(4 days ago) Summary: Drug interactions are reported among people who take Paracetamol and Apixaban. Common interactions include dizziness among females and confusional state among males. The phase IV clinical study analyzes what interactions people who take Paracetamol and Apixaban have. It is created by eHealthMe based on reports of 1,289 people who take

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Apixaban: Mechanism of Action & Pharmacokinetics Study.com

(3 days ago) Apixaban is an anticoagulant drug: it interrupts the coagulation process. The coagulation process consists of four main steps: Contraction of a vessel ; Formation of platelet plug ;

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