Clopidogrel Bisulfate Drug
Listing Websites about Clopidogrel Bisulfate Drug
Plavix (clopidogrel bisulfate) Generic, Side Effects
(1 days ago) Clopidogrel bisulfate (Plavix) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot.Clopidogrel prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors.
Plavix (clopidogrel bisulfate) 75 mg Tablets.
(5 days ago) Please refer to your supplemental new drug application dated June 17, 2009, received June 17, 2009, submitted under section 505(b)(1) of the Federal Food, Drug, and Cosmetic Act (FDCA) for Plavix (clopidogrel bisulfate) 75 mg Tablets. We also acknowledge receipt of your submissions dated September 15, October 6, 22, 30, November 19,
Clopidogrel Uses, Side Effects & Warnings - Drugs.com
(2 days ago) Clopidogrel side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Clopidogrel increases your risk of bleeding, which can be severe or life-threatening.
Side Effects of Plavix (Clopidogrel Bisulfate), Warnings, Uses
(8 days ago) Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular …
FDA Drug Safety Communication: Reduced effectiveness of
(6 days ago) Information on Clopidogrel Bisulfate (marketed as Plavix) Podcast for Healthcare Professionals: Reduced effectiveness of Plavix in patients who are poor metabolizers of the drug Content current as of:
Drug Interactions: Clopidogrel-Proton Pump Inhibitor
(6 days ago) Drug Interactions: Clopidogrel-Proton Pump Inhibitor Interaction: An Update. This column is an update to the April 2008 column that discussed the possible interaction between clopidogrel and proton pump inhibitors-new studies and data are brought into perspective. Drs. Horn and Hansten are both professors of pharmacy at the University of
DailyMed - CLOPIDOGREL BISULFATE tablet
(3 days ago) Clopidogrel bisulfate can increase the systemic exposure to drugs that are primarily cleared by CYP2C8, thereby needing dose adjustment and appropriate monitoring. Clopidogrel bisulfate increased repaglinide exposures by 3.9-fold to 5.1-fold [see Clinical Pharmacology ( 12.3)].
Clopidogrel bisulfate DrugBank Online
(2 days ago) Name Clopidogrel bisulfate Drug Entry Clopidogrel. Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. 3,9 Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established
DailyMed - CLOPIDOGREL- clopidogrel bisulfate tablet, film
(3 days ago) The metabolism of clopidogrel can also be impaired by drugs that inhibit CYP2C19, such as omeprazole or esomeprazole. Avoid concomitant use of clopidogrel bisulfate with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of clopidogrel bisulfate [see Drug Interactions (7.1)].
DailyMed - CLOPIDOGREL BISULFATE powder
(3 days ago) Drug names that are ambiguous or not compatible with the RxNorm system, such as multivitamins with more than 4,000 characters in their names, are also out of scope. Get Label RSS Feed for this Drug CLOPIDOGREL BISULFATE powder
Plavix (clopidogrel bisulfate) Side Effects & Drug
(2 days ago) Plavix (clopidogrel bisulfate) is an antiplatelet drug used to prevent strokes, heart attacks, and death in individuals who have had a previous stroke, unstable angina, heart attack or have peripheral arterial disease (PAD).. The combination of Plavix and aspirin is better than aspirin or Plavix alone in preventing another heart attack but the risk of bleeding is higher.
clopidogrel bisulfate - Drug Summary - PDR.Net
(4 days ago) Ticlopidine: (Moderate) Because clopidogrel inhibits platelet aggregation, a potential additive risk for bleeding exists if clopidogrel is given in combination with other drugs that affect hemostasis such as platelet inhibitors. Also, coadministration of clopidogrel and ticlopidine should be avoided.
DailyMed - PLAVIX- clopidogrel bisulfate tablet, film coated
(3 days ago) PLAVIX (clopidogrel bisulfate) 75-mg tablets are available as pink, round, biconvex, film-coated tablets debossed with "75" on one side and "1171" on the other. Tablets are provided as follows: NDC 63653-1171-6 bottles of 30 NDC 63653-1171-1 bottles of 90 NDC 63653-1171-5 bottles of 500 NDC 63653-1171-3 blisters of 100.
Plavix (clopidogrel bisulfate) dose, indications, adverse
(9 days ago) Omeprazole is an inhibitor of CYP2C19. In clinical studies, use of omeprazole significantly reduced the antiplatelet activity of clopidogrel when administered concomitantly or 12 hours apart. (Moderate) Although aspirin may be used in combination with clopidogrel, both drugs are associated with bleeding.
DailyMed - PLAVIX- clopidogrel bisulfate tablet, film coated
(3 days ago) Plavix (clopidogrel bisulfate) is a thienopyridine class inhibitor of P2Y 12 ADP platelet receptors. Chemically it is methyl (+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4 H)-acetate sulfate (1:1). The empirical formula of clopidogrel bisulfate is C 16 H 16 ClNO 2 S•H 2 SO 4 and its molecular weight is 419.9.
NDC Active Ingredient Clopidogrel Bisulfate
(Just Now) NDC Active Ingredient Clopidogrel Bisulfate. List of the 77 NDC products with the active ingredient Clopidogrel Bisulfate. Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat
Side effects, images, and drug details for Clopidogrel
(3 days ago) Clopidogrel may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure clopidogrel is right for you. This medicine is not expected to harm an unborn baby. However, taking clopidogrel within 1 week before childbirth can cause bleeding in the
Mixture of clopidogrel bisulfate and magnesium oxide
(3 days ago) The yield of clopidogrel (molecular form) recovered from test solutions C and D (using a suspension of clopidogrel bisulfate tablets alone) was 73.9 ± 3.7 mg (n = 3), which was within the stipulated range, whereas that from test solutions E and F (using a cosuspension of clopidogrel bisulfate and MgO tablets) was lower (62.1 ± 3.0 mg, n = 3
Clopidogrel - Wikipedia
(1 days ago) Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Onset of effects is about two hours and lasts for five days.
Clopidogrel: Uses, Interactions, Mechanism of Action
(7 days ago) A 75mg oral dose of clopidogrel is 50% absorbed from the intestine. 9 Clopidogrel can be taken with or without food. 9 A meal decreases the AUC of the active metabolite by 57%. 9 The active metabolite of clopidogrel reaches a maximum concentration after 30-60 minutes. 9 Clopidogrel reached a C max of 2.04±2.0ng/mL in 1.40±1.07h. 5
PLAVIX DESCRIPTION - Food and Drug Administration
(5 days ago) Plavix for oral administration is provided as either pink, round, biconvex, debossed, film-coated tablets containing 97.875 mg of clopidogrel bisulfate which is the molar equivalent of 75 mg of clopidogrel base or pink, oblong, debossed film-coated tablets containing 391.5 mg of
Clopidogrel Advanced Patient Information - Drugs.com
(3 days ago) Clopidogrel is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Clopidogrel may also increase the chance of serious bleeding in some people. Clopidogrel is available only with your doctor's prescription.
Compare Clopidogrel Bisulfate prices and find coupons that
(8 days ago) Clopidogrel Bisulfate Prices and Coupons. Brand Names: Plavix. Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood
Clopidogrel bisulfate C16H18ClNO6S2 - PubChem
(3 days ago) 2021-10-09. Create. 2005-06-24. Clopidogrel Bisulfate is a thienopyridine with antiplatelet activity. Clopidogrel bisulfate irreversibly alters the platelet receptor for adenosine diphosphate ( ADP ), thereby blocking the binding of ADP to its receptor, inhibiting ADP -mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting
Clopidogrel bisulfate and Clopidogrel drug interactions, a
(7 days ago) Drug interactions are reported among people who take Clopidogrel bisulfate and Clopidogrel. Common interactions include atrial fibrillation among females and vomiting among males. The phase IV clinical study analyzes what interactions people who take Clopidogrel bisulfate and Clopidogrel have.
Plavix (Clopidogrel) - Side Effects, Interactions, Uses
(3 days ago) Find everything you need to know about Plavix (Clopidogrel), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Plavix (Clopidogrel) at
Design, development and characterization of Clopidogrel
(1 days ago) Clopidogrel bisulfate is an antiplatelet drug, undergoes hepatic phases from the below mentioned formula . first pass metabolism and low oral bioavailability (50%) . Hence, it is suitable for formulation as a transdermal patch. Drug molecules Concentration of drug in non aqueous phase Partition coefficient = in contact with the skin
Clopidogrel: Some Drugs May Reduce Its Effectiveness
(7 days ago) Clopidogrel represents a ratherunique risk for drug interactions, however.It is a prodrug that requires metabolicconversion to a thiol metabolitethat binds to the platelet adenosinediphosphate receptor and reduces theability of platelets to aggregate.
Clopidogrel (Oral Route) Description and Brand Names
(2 days ago) Drug information provided by: IBM Micromedex. US Brand Name. Plavix; Descriptions. Clopidogrel is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients with acute coronary syndrome (ACS), to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with
clopidogrel bisulfate - GLOWM
(8 days ago) • Drug is usually used in patients who are hypersensitive or intolerant to aspirin. • If patient is to undergo surgery and an antiplatelet effect isn’t desired, drug should be stopped 7 days before surgery. • Monitor patient for unusual bleeding or bruising. ALERT Don’t confuse Plavix (clopidogrel…
PRODUCT MONOGRAPH CLOPIDOGREL
(9 days ago) Clopidogrel bisulfate is a pro-drug, which requires metabolism by the hepatic cytochrome CYP2C19 to form the active thiol metabolite. The function of this enzyme can be compromised, either through direct drug inhibition or dysfunctional genetic variants that lower enzyme activity,
Clopidogrel - an overview ScienceDirect Topics
(9 days ago) Clopidogrel is a prodrug requiring bioactivation by multiple cytochrome P450 (CYP450) enzymes. As shown in Fig. 6.2, clopidogrel is a p-glycoprotein substrate, and once absorbed, the majority of clopidogrel is eliminated via esterases. The remaining drug requires conversion via a two-step process to its active form.
FAQ about Clopidogrel Bisulfate Drug
Is generic clopidogrel equivalent to the brand-name drug?
All of the generic clopidogrel versions currently available have an "AB" rating, meaning they should be equivalent to Plavix. However, generic medications are allowed to have different inactive ingredients than the brand-name medication.
What is another name for clopidogrel?
Clopidogrel, sold under the trade name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy).
What is the generic of clopidogrel?
Generic Name: Clopidogrel. Generic for Plavix* (Clopidogrel) is used to prevent blood clots in people with recent heart attack or stroke. Clopidogrel is in a class of medications called antiplatelet drugs. This medication helps smooth flow of blood in your body, thereby preventing harmful blood clots.