Listing Websites about Lovastatin Drug
Lovastatin Uses, Side Effects & Warnings - Drugs.com
(1 days ago) Lovastatin side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Lovastatin can cause the breakdown of muscle tissue, which can lead to kidney failure.
Lovastatin: Basics, Side Effects & Reviews
(1 days ago) Drug interactions. Risk factors: Taking with certain drugs that raise the amount of lovastatin in the body; Combining certain medications can raise the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist before taking any new medications. Muscle weakness (autoimmune)
Lovastatin: Uses, Interactions, Mechanism of Action
(7 days ago) Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. 1 Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal
Lovastatin: Side Effects, Dosage, Uses, and More
(2 days ago) Lovastatin oral tablet is a statin used to prevent and treat coronary heart disease, and to treat high cholesterol. It's available as a generic drug and as the brand-name drug Altoprev. The tablet
Lovastatin (Oral Route) Side Effects - Mayo Clinic
(2 days ago) difficulty with moving. fever. frequent urge to urinate. headache. joint pain or swelling. lower back or side pain. muscle ache, cramp, spasm, stiffness, pain, tenderness, or weakness. pain or tenderness around the eyes and cheekbones. stuffy or runny nose.
Lovastatin (lovastatin) dose, indications, adverse effects
(3 days ago) Although other drugs were in use concurrently, a drug interaction between danazol and lovastatin is suspected since danazol (CYP3A4 inhibitor) is known to inhibit lovastatin metabolism. If concurrent use of lovastatin and danazol is desired, carefully weigh the benefit of lovastatin against the risk of myopathy and rhabdomyolysis.
Mevacor Tablets Label - Food and Drug Administration
(5 days ago) C-labeled lovastatin in man, 10% of the dose was excreted in urine and 83% in feces. The latter represents absorbed drug equivalents excreted in bile, as well as any unabsorbed drug. Plasma concentrations of total radioactivity (lovastatin plus . 14. C-metabolites) peaked at 2 hours and declined rapidly to about 10% of peak by 24 hours postdose.
List of Statins + Uses, Types & Side Effects - Drugs.com
(6 days ago) Pravastatin and fluvastatin have a lower risk of drug interactions because they are not metabolized by cytochrome p450 3A4. Atorvastatin and fluvastatin are considered the most cost-effective statins. Grapefruit juice increases levels of atorvastatin, lovastatin, and simvastatin, which may increase the risk of side effects. Grapefruit juice
Lovastatin « New Drug Approvals
(1 days ago) Lovastatin (Merck’s Mevacor) is a statin drug, used for lowering cholesterol ( hypolipidemic agent) in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring compound found in food such as …
Lovastatin FDA Warnings & Precautions Healthgrades
(4 days ago) Lovastatin produced optic nerve degeneration (Wallerian degeneration of retinogeniculate fibers) in clinically normal dogs in a dose-dependent fashion starting at 60 mg/kg/day, a dose that produced mean plasma drug levels about 30 times higher than the mean drug level in humans taking the highest recommended dose (as measured by total enzyme
Lovastatin Medicare Coverage and Co-Pay Details - GoodRx
(1 days ago) Lovastatin is an inexpensive drug used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. This drug is slightly less popular than comparable drugs. Lovastatin is only available as a generic drug; all brands have been discontinued.
Lovastatin (Oral Route) Description and Brand Names - Mayo
(1 days ago) Drug information provided by: IBM Micromedex. US Brand Name. Altoprev; Mevacor; Descriptions. Lovastatin is used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. This medicine may also help prevent medical problems (eg, chest pain, heart attack, stroke) caused by fat clogging the blood vessels.
lovastatin Side Effects, Uses, Interactions, Pictures
(1 days ago) LOVASTATIN (LOE va sta tin) is known as a HMG-CoA reductase inhibitor or 'statin'. It lowers the level of cholesterol in the blood. This drug may also reduce the risk of heart attack or other health problems in patients with risk factors for heart disease.
Statin side effects: Weigh the benefits and risks - Mayo
(1 days ago) Switch to another statin drug. It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other …
Lovastatin Prices, Coupons & Savings Tips - GoodRx
(3 days ago) Lovastatin is an inexpensive drug used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. This drug is slightly less popular than comparable drugs. Lovastatin is only available as a generic drug; all brands have been discontinued.
Lovastatin Information, Side Effects, Warnings and Recalls
(4 days ago) Strong inhibitors of CYP3A4: Lovastatin, like several other inhibitors of HMG-CoA reductase, is a substrate of cytochrome P450 3A4 (CYP3A4). Certain drugs which inhibit this metabolic pathway can raise the plasma levels of lovastatin and may increase the risk of myopathy.
Lovastatin (Mevacor) - Side Effects, Interactions, Uses
(7 days ago) Lovastatin is used to lower the risk of stroke, heart attack, and other heart complications in adults with diabetes, coronary heart disease, or other risk factors. Lovastatin may also be used for
Lovastatin - The first statin medications
(4 days ago) Lovastatin. Lovastatin (brand names Mevacor, Altocor, and Altoprev) was the first statin approved for human use. In 1978, lovastatin (originally called mevinolin) was isolated from the fungus Aspergillus terreus by scientists working Merck Research Laboratories. Merck subsequently developed simvastatin, which is a close chemical derivative and
lovastatin oral Interactions with Other Medication
(1 days ago) Does LOVASTATIN Interact with other Medications? Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more
Lovastatin: Generic, Uses, Side Effects, Dosages
(9 days ago) Lovastatin is a cholesterol-lowering medication called a statin prescribed to treat elevated blood cholesterol levels.. Lovastatin should be used in addition to dietary modifications as part of a treatment plan to lower cholesterol levels when the response to diet and other non-pharmacological measures alone have been inadequate to reduce cardiovascular risk.
Dangers of Statin Drugs: What You Haven’t Been Told About
(4 days ago) Statin drugs are very expensive–a course of statins for a year costs between $900 and $1400. They constitute the mostly widely sold pharmaceutical drug, accounting for 6.5 percent of market share and 12.5 billion dollars in revenue for the industry. Your insurance company may pay most of that cost, but consumers always ultimately pay with
Statins: Are these cholesterol-lowering drugs right for
(9 days ago) Very rarely, high-dose statin use can cause muscle cells to break down and release a protein called myoglobin into the bloodstream. This can lead to severe muscle pain and kidney damage. Liver damage. Occasionally, statin use causes an increase in liver enzymes. If the increase is mild, you can continue to take the drug.
Lovastatin Drug Information PDR.net
(4 days ago) The Related Drug Information Index provides comprehensive access to all drug information related to a specific drug Types of content include full prescribing information, drug summaries, Full Prescribing Information Continuing Medication Education (Full PI CME), Medication Guides, Risk Evaluation and Mitigation Strategies (REMS Summaries), REMS Continuing Medication Education (REMS CME), and
Lovastatin Healthgrades (tablet)
(5 days ago) Lovastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, lovastatin should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus (see PRECAUTIONS, Pregnancy).
DailyMed - LOVASTATIN tablet
(3 days ago) Lovastatin undergoes extensive first-pass extraction in the liver, its primary site of action, with subsequent excretion of drug equivalents in the bile. As a consequence of extensive hepatic extraction of lovastatin, the availability of drug to the general circulation is low and variable.
Lovastatin (Altoprev, Mevacor) Davis’s Drug Guide
(2 days ago) Download the Davis's Drug Guide app by Unbound Medicine. 2. Select Try/Buy and follow instructions to begin your free 30-day trial. You can cancel anytime within the 30-day trial, or continue using Davis's Drug Guide to begin a 1-year subscription ($39.95) lovastatin. General.
Lovastatin C24H36O5 - PubChem
(2 days ago) Lovastatin is the delta-lactone of mevinolinic acid and is produced by fermentation of Aspergillus terreus. The drug has also been isolated as a fermentation metabolite of Monascus ruber. American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 1854.
lovastatin Drug Interactions - Epocrates Web
(9 days ago) use alternative or monitor ECG, CK, myopathy sx; adjust lovastatin max dose to 40 mg/day: combo may incr. levels of both drugs, risk of QT prolongation, cardiac arrhythmias, myopathy, rhabdomyolysis, other adverse effects (hepatic metab. inhibited, P-gp-mediated transport inhibited)
Lovastatin - an overview ScienceDirect Topics
(Just Now) Lovastatin. Lovastatin is a fungal polyketide employed as a cholesterol-lowering drug that inhibits (3S)-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyses the synthesis of mevalonate, which is the immediate precursor of cholesterol and is the target of all of the drugs …
DGIdb - LOVASTATIN Drug Record
(7 days ago) Tirkkonen et al., 2008, Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study., Drug Saf Ohno et al., 2007, General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs., Clin Pharmacokinet
Transcriptome-based identification of lovastatin as a
(1 days ago) By GSEA, lovastatin downregulated genes that are involved in stemness and invasiveness in mammary tumors, corroborating our in vitro findings. Conclusion: Lovastatin is a breast CSC-targeting drug. The inhibition of HMGCR might develop new adjuvant therapeutic strategies for breast tumors.
Lovastatin - Drug
(1 days ago) Buckingham R (ed). Lovastatin. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 24/10/2013. FDA Drug Safety Communication: Interactions Between Certain HIV or Hepatitis C Drugs and Cholesterol-Lowering Statin Drugs Can Increase The Risk of Muscle Injury.
Can I use red yeast rice instead of a statin to lower my
(1 days ago) The Food and Drug Administration (FDA) has blocked the sale of red yeast rice supplements that contain enough of the active ingredient to make them as effective as lovastatin because they haven't undergone the drug approval process. Unlike FDA-approved drugs, supplements can be sold without proof of effectiveness and purity.
(6 days ago) Lovastatin is a member of the HMG-CoA reductase inhibitor family of drugs, which blocks the body's production of cholesterol. Lovastatin is used to lower high cholesterol levels.Cholestin, a dietary supplement advertised to help maintain healthy cholesterol, but not to lower high cholesterol, contains several HMG-CoA reductase inhibitor chemicals, including lovastatin.
Statin-associated polymyositis following omeprazole
(1 days ago) Statins are an extensively used class of drugs, and myopathy is an uncommon, but well-described side effect of statin therapy. Inflammatory myopathies, including polymyositis, dermatomyositis, and necrotizing autoimmune myopathy, are even more rare, but debilitating, side effects of statin therapy that are characterized by the persistence of symptoms even after discontinuation of the drug.
Statin - Wikipedia
(6 days ago) Records exist of over 250,000 people treated from 1998 to 2001 with the statin drugs atorvastatin, cerivastatin, fluvastatin, lovastatin, pravastatin, and simvastatin. The incidence of rhabdomyolysis was 0.44 per 10,000 patients treated with statins other than cerivastatin.
FAQ about Lovastatin Drug
When to take lovastatin?
The regular tablet usually is taken once or twice a day with meals. The extended-release tablet usually is taken once a day at bedtime. Take lovastatin at around the same time(s) every day.
What are the side effects of lovastatin?
Commonly reported side effects of lovastatin include: increased creatine phosphokinase in blood specimen and increased serum transaminases.
Does lovastatin cause tiredness?
Lovastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.
What is Lovastatin used for?
The primary uses of lovastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease.