Rofecoxib Drug

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rofecoxib (Vioxx): Drug Facts, Side Effects and Dosing

(9 days ago) WebWhat is rofecoxib, and how does it work (mechanism of action)? Rofecoxib is a nonsteroidal anti-inflammatory drug ( NSAID) that is used to treat pain, particularly the …

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Rofecoxib - Wikipedia

(9 days ago) OverviewMode of actionEfficacySide effectsWithdrawalFDA positionLitigationPossible return to marketRofecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It was marketed by Merck & Co. to treat osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, acute pain conditions, migraine, and dysmenorrhea. Rofecoxib was approved in the US by the US Food and Drug Administration (FDA) in May 1999, and was marketed under the brand names Vioxx, Ceoxx, …

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Vioxx (Rofecoxib): Uses, Dosage, Side Effects, Interactions …

(7 days ago) WebVIOXX® (rofecoxib) is a nonsteroidal anti-inflammatory drug ( NSAID ). The chemical name is 4- [4 (methylsulfonyl)phenyl]-3-phenyl-2 (5H)-furanone. The molecular weight is 314.36. The empirical …

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Rofecoxib Tablet - Uses, Side Effects, and More - WebMD

(3 days ago) WebFind patient medical information for rofecoxib oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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Rofecoxib: Uses, Interactions, Mechanism of Action

(7 days ago) Web1358 rows · Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Unlike celecoxib, rofecoxib lacks a …

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Vioxx: Side Effects, Dosage & Uses - Drugs.com

(2 days ago) WebVioxx is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and certain forms of juvenile rheumatoid arthritis; to …

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Rofecoxib C17H14O4S - PubChem

(1 days ago) Webrofecoxibum Rofecoxib (JAN/USAN/INN) Rofecoxib [USAN:INN:BAN] 3-Phenyl-4- (4- (methylsulfonyl)phenyl))-2 (5H)-furanone Rofecoxib [USAN] 4- (4-methylsulfonylphenyl) …

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Rofecoxib Side Effects: Common, Severe, Long Term

(3 days ago) WebApplies to rofecoxib: oral suspension, oral tablet. Gastrointestinal Gastrointestinal side effects have included diarrhea, dyspepsia, epigastric discomfort, heartburn, and nausea. …

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Vioxx Treatment for Arthritis & Recall for Patient Deaths

(2 days ago) WebVioxx treats Rheumatoid Arthritis, pictured above When Vioxx (rofecoxib) received its FDA approval in 1999, it was the second drug of its kind in a relatively new class of painkiller drugs called selective nonsteroidal anti …

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Side Effects of Vioxx (Rofecoxib), Warnings, Uses - RxList

(7 days ago) WebOur Vioxx (rofecoxib) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this …

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Failing the Public Health — Rofecoxib, Merck, and the FDA

(9 days ago) WebThe pivotal trial for rofecoxib involved 8076 patients with rheumatoid arthritis and demonstrated that this coxib had lower gastrointestinal toxicity than naproxen. 1 …

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Rofecoxib - an overview ScienceDirect Topics

(7 days ago) WebThe drug is administered orally, its bioavailability is 93%, and 87% of the absorbed dose is bound to plasma proteins. 136 The metabolism of rofecoxib in the liver yields …

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Rofecoxib - LiverTox - NCBI Bookshelf

(5 days ago) WebRofecoxib is a nonsteroidal antiinflammatory drug (NSAID) that selectively inhibits cyclooxgenase-2 (Cox-2), which was used in the therapy of chronic arthritis and mild-to-moderate musculoskeletal pain. …

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North Bergen Drug and Alcohol Addiction Treatment Centers in …

(4 days ago) WebDetox helps people diagnosed with a substance use disorder taper off drugs or alcohol, relieve discomfort, and stabilize. Once detox is complete, people may then enter …

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Drug Testing Locations North Bergen, NJ (800) 221-4291

(3 days ago) WebSame day service is available and testing centers are within minutes of your home or office. (800) 221-4291. Schedule Your Test. Tests are administered utilizing urine, oral/ saliva, …

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T & F Drugs Incorporated Company Profile North Bergen, NJ

(7 days ago) WebFind company research, competitor information, contact details & financial data for T & F Drugs Incorporated of North Bergen, NJ. Get the latest business insights from Dun & …

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FAQ about Rofecoxib Drug

What is rofecoxib used for?

Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, particularly the pain of osteoarthritis and menstrual cramps. Prostaglandins are chemicals that are important in promoting inflammation and its signs--pain, fever, swelling and tenderness.

What is Vioxx (rofecoxib) used for?

Last reviewed on RxList 02/17/2017. Vioxx (rofecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and certain forms of juvenile rheumatoid arthritis; to manage acute pain in adults; to treat migraines; and to treat menstrual pain.

Is rofecoxib an NSAID?

Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Unlike celecoxib, rofecoxib lacks a sulfonamide chain and does not require CYP450 enzymes for metabolism.

Is rofecoxib selective for COX-2?

As rofecoxib is selective for COX-2, it may be potentially associated with a decreased risk of certain adverse events, but more data is needed to fully evaulate the drug. The anti-inflammatory, analgesic, and antipyretic effects of NSAIDs appear to result from the inhibition of prostaglandin synthesis.