Listing Websites about Rofecoxib Drug
rofecoxib (Vioxx): Drug Facts, Side Effects and Dosing
(9 days ago) Rofecoxib is a nonsteroidal anti-inflammatory drug that is used to treat pain, particularly the pain of osteoarthritis and menstrual cramps. Prostaglandins are chemicals that are important in …
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Vioxx: Side Effects, Dosage & Uses - Drugs.com
(2 days ago) unexplained weight gain; swelling or water retention; unusual fatigue or lethargy; a skin rash or itching; yellowing of your skin or eyes; "flu-like" symptoms; or. unusual bruising or bleeding. Other, less serious side effects may be more likely to occur. Continue to take Vioxx and talk to your doctor if you experience.
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FAQ about Rofecoxib Drug
What is the chemical name for rofecoxib?
VIOXX® (rofecoxib) is a nonsteroidal anti-inflammatory drug (NSAID). The chemical name is 4-[4(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. The molecular weight is 314.36.
What is the mechanism of action of rofecoxib?
Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic therapeutic effects. It has been proposed that rofecoxib inhibits the activity of the enzyme cyclooxygenase-2 (COX-2), resulting in a decreased formation of precursors of prostaglandins.
Is rofecoxib available by prescription?
Rofecoxib was available by prescription in both tablet-form and as an oral suspension. Rofecoxib gained widespread use among physicians treating patients with arthritis and other conditions causing chronic or acute pain. Worldwide, over 80 million people were prescribed rofecoxib at some time.
Is rofecoxib a COX-2 inhibitor?
Rofecoxib is a selective COX-2 inhibitor, or "coxib". Though the class of coxibs includes several agents, there are varying degrees of COX-2 selectivity among them, with celecoxib (Celebrex) being the least COX-2 selective, and rofecoxib (Vioxx), valdecoxib (Bextra), and etoricoxib (Arcoxia), being highly COX-2 selective.