Simvastatin Drug

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Simvastatin Uses, Dosage & Side Effects -

(8 days ago) Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

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Simvastatin Oral: Uses, Side Effects, Interactions

(4 days ago) Simvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in …

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Simvastatin Side Effects, Dosage, Usage, and More

(3 days ago) Simvastatin is a prescription drug. It comes in two forms: a tablet and a suspension. Both forms are taken by mouth. Simvastatin oral tablet is available as the brand-name drug Zocor. It’s also

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Simvastatin (Oral Route) Side Effects - Mayo Clinic

(3 days ago) skin rash, hives, or itching. sores, ulcers, or white spots in the mouth or on the lips. tightness in the chest. unusual bleeding or bruising. upper right abdominal or stomach pain. weakness in the arms, hands, legs, or feet. yellow eyes or skin. Some side effects may occur that usually do not need medical attention.

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Simvastatin and Alcohol/Food Interactions -

(6 days ago) simvastatin Alcohol (Ethanol) Moderate Drug Interaction. Simvastatin may cause liver problems and using it with substantial quantities of ethanol may increase that risk. You should limit the use of alcohol while being treated with these medications. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding

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Statin side effects: Weigh the benefits and risks - Mayo

(1 days ago) Switch to another statin drug. It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses. Change your dose.

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Ezetimibe and simvastatin Uses, Side Effects -

(6 days ago) What is ezetimibe and simvastatin? Ezetimibe reduces the amount of cholesterol absorbed by the body. Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins.". Ezetimibe and simvastatin is a combination medicine that is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" …

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Apolipoprotein B, Triglyceride-Rich Lipoproteins, and Risk

(1 days ago) Higher apo-B, triglycerides, ratio of triglyceride to HDL cholesterol, and triglyceride-rich lipoprotein cholesterol concentrations were associated with increased risk of atherosclerotic vascular events in CKD. Reducing triglyceride-rich lipoproteins using novel therapeutic agents could potentially …

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A useful tool for drug interaction evaluation: The

(6 days ago) that drugdrug interactions (DDIs) represent 3–5 per cent of all in-hospital medication errors and tatin, midazolam, saquinavir, sildenafil, simvastatin, triazolam and vardenafil. Broad applicability of the above proposal rests on the assumption that the classification of a CYP3A inhibitor would be independent of the sensitive

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simvastatin Uses, Side Effects, Dosage & Interactions

(3 days ago) Simvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).. Simvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary …

Category:  Heart,  Diabetes Detail Drugs

Simvastatin for cholesterol treatment - uses and risks

(5 days ago) Simvastatin . Simvastatin is the second-most widely used cholesterol drug. Over 48 million prescriptions are filled every year in the US alone.. Simvastatin is available in 5, 10, 20, 40, and 80 mg tablets. The daily dosing range is 5-80 mg with a recommended starting dose of 20 to 40 mgs daily, taken with meals.

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Dangers of Statin Drugs: What You Haven’t Been Told About

(4 days ago) Statin drugs are very expensive–a course of statins for a year costs between $900 and $1400. They constitute the mostly widely sold pharmaceutical drug, accounting for 6.5 percent of market share and 12.5 billion dollars in revenue for the industry. Your insurance company may pay most of that cost, but consumers always ultimately pay with

Category:  Pharmaceutical Detail Drugs

Simvastatin: Generic, Uses, Side Effects, Dosages

(9 days ago) Simvastatin is a, FDA approved prescription medication that is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol in the blood.It belongs to a group of drugs known as "statins."Statins are medications that work by reducing the amount of cholesterol made by the liver.

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Simvastatin C25H38O5 - PubChem

(3 days ago) Simvastatin is a member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.It has a role as an EC (anthrax lethal factor endopeptidase) inhibitor, a prodrug, an EC

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Zocor (Simvastatin) Oral: Uses, Side Effects, Dosages

(1 days ago) What Is Zocor? Zocor (simvastatin) is a prescription drug used with diet and exercise to lower cholesterol. Zocor contains the active ingredient simvastatin. This medication is in a drug class called HMG CoA reductase inhibitors. This class is also known as statins.

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Simvastatin - LiverTox - NCBI Bookshelf

(5 days ago) Simvastatin is available generic forms and under the commercial name of Zocor in tablets of 5, 10, 20, 40 and 80 mg. the recommended dose is 5 to 80 mg daily based upon tolerability and lipid levels. Simvastatin is also available as a fixed combination with ezetimibe under the brand name Vytorin. Common side effects include muscle cramps, joint

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Simvastatin: Uses, Interactions, Mechanism of Action

(7 days ago) Generic Name Simvastatin DrugBank Accession Number DB00641 Background. Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus.It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting …

Category:  Medications Detail Drugs

Simvastatin (Zocor): Basics, Side Effects & Reviews

(2 days ago) Simvastatin (Zocor) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.

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simvastatin Nursing Considerations & Management - RNpedia

(Just Now) Drug Name Generic Name : simvastatin Brand Name: Apo-Simvastatin (CAN), Gen-Simvastatin (CAN), CO Simvastatin (CAN), Novo-Simvastatin (CAN), ratio-Simvastatin (CAN), Zocor Classification: Antihyperlipidemic, HMG-CoA reductase inhibitor Pregnancy Category X Dosage & Route Available forms : Tablets—5, 10, 20, 40, 80 mg ADULTS Initially, 20 mg PO; …

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A new therapeutic effect of simvastatin revealed by

(1 days ago) Simvastatin dramatically reduced damage and enhanced muscle function in dystrophic (mdx) mice. Long-term simvastatin treatment vastly improved overall muscle health in mdx mice, reducing plasma creatine kinase activity, an established measure of muscle damage, to near-normal levels. This reduction was accompanied by reduced inflammation, more

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Statins: Are these cholesterol-lowering drugs right for you?

(Just Now) Simvastatin (Zocor) Sometimes, a statin is combined with another heart medication. Examples are atorvastatin-amlodipine (Caduet) and ezetimibe-simvastatin (Vytorin).

Category:  Heart Detail Drugs

Zocor (Simvastatin): Uses, Dosage, Side Effects

(7 days ago) ZOCOR should be administered to women of childbearingage only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, ZOCOR should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus [see Use In Specific Populations]. Nursing mothers.

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[Medication management: Simvastatin and Amlodipin - a

(1 days ago) The clinical relevance of the drug-drug interaction simvastatin and amlodipine is appraised controversially by german simvastatin Summary of Product Characteristics (SPCs) and different drug interaction databases. Results of clinical trials have shown that simultaneous administration of simvastatin

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Simvastatin Drug Information - Indications, Dosage, Side

(5 days ago) This medication is an HMG-CoA reductase inhibitor, also known as a "statin", used for lowering high cholesterol and triglycerides in certain patients with appropriate diet.

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Simvastatin - Drug

(5 days ago) Simvastatin, a prodrug, is converted to its active metabolite simvastatin acid (SVA), which is a substrate of the organic anion transporter protein OATP1B1. OATP1B1 mediates the hepatic uptake of statins and other endogenous compounds (e.g. bilirubin) for subsequent elimination.

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Simvastatin - StatPearls - NCBI Bookshelf

(5 days ago) Simvastatin is an oral HMG-CoA reductase inhibitor indicated as an adjunct to diet. It is a semi-synthetic derivative of lovastatin, the first FDA-approved statin. Simvastatin helps lower cholesterol production and reduce dyslipidemia-associated complications. High concentrations of LDL cholesterol can lead to artery damage, potentially leading to cardiac …

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Drug Interactions with Simvastatin: The Risk Continues

(8 days ago) A number of drugs are known to inhibit OATP1b1 (eg, clarithromycin, erythromycin, cyclosporine, ketoconazole, many protease inhibitors, gemfibrozil) and are known to increase simvastatin concentrations. 5 Note that many OATP1b1 inhibitors are also CYP3A4 inhibitors, which provides the opportunity for a dual mechanism drug interaction with

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Statins: How to Safely Stop Taking These Cholesterol Drugs

(1 days ago) Drugs your doctor could add to your medication regimen while reducing your statin use include ezetimibe, bile acid sequestrants, or niacin. These medications can help manage your cholesterol

Category:  Medications,  Doctor Detail Drugs

Simvastatin - an overview ScienceDirect Topics

(1 days ago) Simvastatin, a FDA approved drug that specifically inhibits HMG-CoA reductase, is a widely prescribed drug to lower LDL cholesterol and triglyceride levels in hyperlipidemia subjects with proven beneficial effects in coronary artery disease. In addition to lipid-lowering property,

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Zocor (simvastatin) dose, indications, adverse effects

(4 days ago) Simvastatin is a substrate for CYP3A4 and the drug transporter organic anion transporting polypeptide (OATP1B1); protease inhibitors are CYP3A4 and OATP inhibitors. Sarilumab: (Moderate) Utilize caution with concomitant use of sarilumab and CYP3A4 substrate drugs, such as simvastatin, where a decrease in effectiveness is undesirable. Monitor

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Simvastatin: Dosage, Mechanism/Onset of Action, Half-Life

(5 days ago) Dosage adjustment for simvastatin with concomitant medications: Note: Patients currently tolerating and requiring a dose of simvastatin 80 mg who require initiation of an interacting drug with a dose cap for simvastatin should be switched to an alternative statin with less potential for drug-drug interaction.

Category:  Medications Detail Drugs

Simvastatin PeaceHealth

(6 days ago) Drug Information. Simvastatin is a member of the HMG-CoA reductase inhibitor family of drugs that blocks the body's production of cholesterol. Simvastatin is used to lower high cholesterol and to reduce the risk of heart attack and death.

Category:  Heart Detail Drugs

simvastatin Pictures & Common Dosing - WellRx

(7 days ago) SIMVASTATIN (SIM va stat in) is a statin. It lowers bad cholesterol and triglyceride levels in the blood. It also increases good cholesterol levels. It is used with lifestyle changes, like diet and exercise. It may be used alone or with other drugs.

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Simvastatin: Uses, Side Effects, and More CareLinx

(1 days ago) Drug classes that have severe interactions with simvastatin (Zocor) are primarily drugs that inhibit a liver enzyme called CYP3A4. Medications that inhibit this enzyme will raise simvastatin, lovastatin, fluvastatin, and atorvastatin to dangerous levels in the blood, with possible harm to the muscles, kidneys, and liver.

Category:  Medications Detail Drugs

Simvastatin and Xarelto drug interactions, a phase IV

(3 days ago) Drug interactions are reported among people who take Simvastatin and Xarelto. Common interactions include cerebral haemorrhage among females and gastrointestinal haemorrhage among males. The phase IV clinical study analyzes what interactions people who take Simvastatin and Xarelto have. It is created by eHealthMe based on reports of 5,570

Category:  Health Detail Drugs


(1 days ago) start, stop, or change the dose of any drug without checking with Simvastatin 2/9. your doctor. What are some things I need to know or do while I take this drug? Tell all of your health care providers that you take this drug. This includes your …

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(9 days ago) Tirkkonen et al., 2008, Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study., Drug Saf Cheung et al., 2001, Plasma phospholipid transfer protein activity in patients with low HDL and cardiovascular disease treated with simvastatin and niacin., Biochim.

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SIMVASTATIN Drug BNF content published by NICE

(5 days ago) Simvastatin 10 mg tablets can be sold to the public to reduce risk of first coronary event in individuals at moderate risk of coronary heart disease (approx. 10–15 % risk of major event in 10 years), max. daily dose 10 mg and pack size of 28 tablets; treatment should form part of a programme to reduce risk of coronary heart disease.

Category:  Heart Detail Drugs

Simvastatin and Ibuprofen drug interactions, a phase IV

(5 days ago) Drug interactions are reported among people who take Simvastatin and Ibuprofen. Common interactions include dizziness among females and chronic kidney disease among males. The phase IV clinical study analyzes what interactions people who …

Category:  Health Detail Drugs

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FAQ about Simvastatin Drug

What are side effects of taking simvastatin?

Common simvastatin side effects may include:

  • headache;
  • constipation, nausea, stomach pain; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

Is simvastatin a narcotic?

Narcotic abuse is found among people who take Simvastatin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zolpidem, and have Pain.

What are the side effects of simvastatin 20 mg?

What Are the Side Effects of a 20mg Dose of Simvastatin?

  • Headache. This side effect may be temporary until the body adjusts to this medication. ...
  • Muscle Pain and Weakness. In some cases, this can lead to the development of a muscle disease known as rhabdomyolosis, which may lead to the development of kidney damage.
  • Gastrointestinal Discomfort. ...

When should I take simvastatin?

Simvastatin is usually taken at bedtime or with an evening meal. If you take simvastatin more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results. While using simvastatin, you may need frequent blood tests at your doctor's office.