Bnf.nice.org.uk

Drugs A to Z BNF NICE

Drugs A to Z. Browse drug monographs by A to Z. Drug monographs describe the uses, doses, safety issues, medicinal forms and other considerations involved in the use of a drug.

Actived: Just Now

URL: Bnf.nice.org.uk


Flucloxacillin Drugs BNF NICE

(5 days ago) 250–500 mg 4 times a day for 5–7 days. Adult. 500 mg 4 times a day for 5–7 days. By intramuscular injection. Adult. 250–500 mg every 6 hours. By slow intravenous injection, or by intravenous infusion. Adult. 0.25–2 g every 6 hours.

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Nortriptyline Drugs BNF NICE

(4 days ago) Withdrawal effects may occur within 5 days of stopping treatment with antidepressant drugs; they are usually mild and self-limiting, but in some cases may be severe. The risk of withdrawal symptoms is increased if the antidepressant is stopped suddenly after regular administration for 8 weeks or more. The dose should preferably be reduced

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Tadalafil Drugs BNF NICE

(Just Now) Cialis ® is not prescribable in NHS primary care for the treatment of erectile dysfunction except in men who meet the criteria listed in part XVIIIB of the Drug Tariff (Part XIb of the Northern Ireland Drug Tariff, Part 12 of the Scottish Drug Tariff). The prescription must be endorsed 'SLS'. For more information see Prices in the BNF, under

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Tiotropium Drugs BNF NICE

(1 days ago) For tiotropium. 1 capsule once daily. For Spiriva ® inhalation powder, 1 capsule contains a metered dose of 18 micrograms tiotropium; for Braltus ® inhalation powder, 1 capsule contains a metered dose of 13 micrograms tiotropium. The delivered dose of Spiriva ® and Braltus ® inhalation powder products are the same (10 micrograms); no dose

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Diazepam Drugs BNF NICE

(Just Now) For intravenous infusion (emulsion) (Diazemuls®), give continuously in Glucose 5% or 10%. May be diluted to a max. concentration of 200 mg in 500 mL; max. 6 hours between addition and completion of administration. May be given via drip tubing in …

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Fentanyl Drugs BNF NICE

(9 days ago) Initially 50–100 micrograms (max. per dose 200 micrograms), dose maximum on specialist advice, then 25–50 micrograms as required. By intravenous infusion. Adult. 3–4.8 micrograms/kg/hour, adjusted according to response. Assisted ventilation: analgesia and enhancement of anaesthesia during operation for fentanyl. By slow intravenous injection.

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Topiramate Drugs BNF NICE

(2 days ago) Monotherapy of generalised tonic-clonic seizures or focal seizures with or without secondary generalisation. By mouth. Child 6–17 years. Initially 0.5–1 mg/kg once daily (max. per dose 25 mg) for 1 week, dose to be taken at night, then increased in steps of 250–500 micrograms/kg twice daily, dose to be increased by a maximum of 25 mg

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Flupentixol Drugs BNF NICE

(2 days ago) for use as a hypnotic, unless sleep disorder is due to psychosis or dementia (risk of confusion, hypotension, extrapyramidal side-effects and falls) in patients prone to falls (may cause gait dyspraxia, parkinsonism) if prescribed a phenothiazine (other than prochlorperazine for nausea, vomiting or vertigo; chlorpromazine for relief of

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Semaglutide Drugs BNF NICE

(2 days ago) Semaglutide is a biological medicine. Biological medicines must be prescribed and dispensed by brand name, see Biological medicines and Biosimilar medicines, under Guidance on prescribing; manufacturer advises to record the brand name and batch number after each administration.

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Quetiapine Drugs BNF NICE

(1 days ago) Adult. 50 mg once daily for day 1, dose to be taken at bedtime, then 100 mg once daily for day 2, then 200 mg once daily for day 3, then 300 mg once daily for day 4, then, adjusted according to response; usual dose 300 mg once daily, the rate of dose titration may need to be slower and the daily dose lower in elderly patients; maximum 600 mg

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Sumatriptan Drugs BNF NICE

(2 days ago) Adult 18–65 years. Initially 10–20 mg, dose to be administered into one nostril, followed by 10–20 mg after at least 2 hours if required, to be taken only if headache recurs (patient not responding to initial dose should not take second dose for same attack); maximum 40 mg per day.

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Sulpiride Drugs BNF NICE

(Just Now) There is limited information available on the short- and long-term effects of antipsychotic drugs on the breast-fed infant. Animal studies indicate possible adverse effects of antipsychotic medicines on the developing nervous system. Chronic treatment with antipsychotic drugs whilst breast-feeding should be avoided unless absolutely necessary.

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Dienogest Drugs BNF NICE

(Just Now) Drug actionFor dienogest. Dienogest is a nortestosterone derivative that has a progestogenic effect in the uterus, reducing the production of estradiol and …

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Colecalciferol Drugs BNF NICE

(5 days ago) Other drugs in class; Interactions. View interactions for colecalciferol. Medicinal forms and pricing. There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: tablet, capsule, oral suspension, oral solution, oral drops.

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Mirtazapine Drugs BNF NICE

(2 days ago) Mirtazapine is a presynaptic alpha 2 -adrenoreceptor antagonist which increases central noradrenergic and serotonergic neurotransmission.

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Ranitidine Drugs BNF NICE

(1 days ago) Gastric acid reduction (prophylaxis of acid aspiration) in surgical proceduresfor ranitidine. Initially by intramuscular injection, or by slow intravenous injection. Adult. 50 mg, to be given 45–60 minutes before induction of anaesthesia, intravenous injection diluted to 20 mL and given over at least 2 minutes, alternatively (by mouth) 150 mg

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Erythromycin Drugs BNF NICE

(3 days ago) Susceptible infections in patients with penicillin hypersensitivity (e.g. respiratory-tract infections (including Legionella infection), skin and oral infections, and campylobacter enteritis)for erythromycin. By mouth. Child 1–23 months. 125 mg 4 times a day, total daily dose may alternatively be given in two divided doses, increased to 250

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Ketamine Drugs BNF NICE

(9 days ago) For information on 2015 legislation regarding driving whilst taking certain controlled drugs, including ketamine, see Drugs and driving under Guidance on prescribing. Medicinal forms. There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension

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Sulfasalazine Drugs BNF NICE

(4 days ago) Active rheumatoid arthritis (administered on expert advice)for sulfasalazine. By mouth. Adult. Initially 500 mg daily, increased in steps of 500 mg every week, increased to 2–3 g daily in divided doses, enteric coated tablets to be administered.

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Thiamine Drugs BNF NICE

(9 days ago) Other drugs in classVitamin B group. Cyanocobalamin. Doxylamine with pyridoxine. Hydroxocobalamin. Nicotinamide. Potassium aminobenzoate. Pyridoxine hydrochloride. Vitamin B complex. Vitamin B substances with ascorbic acid.

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Ibuprofen Drugs BNF NICE

(1 days ago) Overdosage with ibuprofen may cause nausea, vomiting, epigastric pain, and tinnitus, but more serious toxicity is very uncommon. Charcoal, activated followed by symptomatic measures are indicated if more than 100 mg/kg has been ingested within the preceding hour. For details on the management of poisoning, see Emergency treatment of poisoning.

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Alprostadil Drugs BNF NICE

(2 days ago) For alprostadil. Initially 250 micrograms, adjusted according to response; usual dose 0.125–1 mg; maximum 2 doses per day; maximum 7 doses per week. 500 micrograms for 1 dose. Apply 300 micrograms, to the tip of the penis, 5–30 minutes before sexual activity; max 1 dose in 24 hours not more than 2–3 times per week.

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Levothyroxine sodium Drugs BNF NICE

(1 days ago) Adult. Initially 25–50 micrograms once daily; adjusted in steps of 25 micrograms every 4 weeks, adjusted according to response; maintenance 50–200 micrograms once daily, dose to be taken preferably 30–60 minutes before breakfast, caffeine-containing liquids (e.g. coffee, tea), or …

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Atorvastatin Drugs BNF NICE

(3 days ago) In chronic kidney disease, for primary and secondary prevention of cardiovascular events [unlicensed starting dose in primary prevention; unlicensed in secondary prevention], initially 20 mg once daily, increased if necessary (on specialist advice if eGFR < 30 mL/minute/1.73 m2); max. 80 mg once daily. See Prescribing in renal impairment.

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Loratadine Drugs BNF NICE

(1 days ago) Side-effects, further information. Non-sedating antihistamines such as loratadine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent.

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Zuclopenthixol Drugs BNF NICE

(5 days ago) if prescribed an antipsychotic drug with moderate or marked antimuscarinic effects (e.g. chlorpromazine, clozapine, flupenthixol, fluphenazine, pipothiazine, promazine and zuclopenthixol) in patients with a history of prostatism or urinary retention (high risk of urinary retention). See also Prescribing in the elderly.

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Tocilizumab Drugs BNF NICE

(2 days ago) There have been reports of rare but serious cases of drug-induced liver injury, including acute liver failure and hepatitis, in patients treated with tocilizumab; some cases required liver transplantation. Serious liver injury was reported from 2 weeks to more than 5 years after initiation of tocilizumab. Healthcare professionals are advised to

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Terbinafine Drugs BNF NICE

(2 days ago) Preparations of terbinafine hydrochloride (maximum 1%) can be sold to the public for use in those over 16 years for external use for the treatment of tinea pedis as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis and cruris as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis, cruris

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Ramipril Drugs BNF NICE

(9 days ago) Prevention of cardiovascular events in patients with atherosclerotic cardiovascular disease or with diabetes mellitus and at least one additional risk factor for cardiovascular diseasefor ramipril. Initially 2.5 mg once daily for 1–2 weeks, then increased to 5 mg once daily for a further 2–3 weeks, then increased to 10 mg once daily.

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Budesonide Drugs BNF NICE

(1 days ago) Adult. 128 micrograms once daily, dose to be administered into each nostril in the morning, alternatively 64 micrograms twice daily, dose to be administered to each nostril, reduce dose when control achieved. Prophylaxis and treatment of allergic and vasomotor rhinitis for budesonide. By intranasal administration.

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Amoxicillin Drugs BNF NICE

(3 days ago) Amoxicillin doses in BNF Publications may differ from those in product literature. Duration of treatment for acute otitis media differs from product literature and adheres to national guidelines. Amoxicillin is used for the treatment of acute exacerbation of bronchiectasis, but …

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Fexofenadine hydrochloride Drugs BNF NICE

(7 days ago) Side-effects, further information. Non-sedating antihistamines such as fexofenadine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent.

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Olanzapine Drugs BNF NICE

(1 days ago) Control of agitation and disturbed behaviour in schizophrenia or maniafor olanzapine. By intramuscular injection. Adult. Initially 5–10 mg for 1 dose; usual dose 10 mg for 1 dose, followed by 5–10 mg after 2 hours if required, maximum 3 injections daily for 3 days; maximum daily combined oral and parenteral dose 20 mg, when one or more

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Chloramphenicol Drugs BNF NICE

(6 days ago) Superficial eye infectionsfor chloramphenicol. Apply 1 drop every 2 hours then reduce frequency as infection is controlled and continue for 48 hours after healing, frequency dependent on the severity of the infection. For less severe infection 3–4 times daily is generally sufficient. Apply 1 drop every 2 hours then reduce frequency as

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Methotrexate Drugs BNF NICE

(3 days ago) With oral use: Methotrexate should be taken once a week in autoimmune conditions and, less commonly, in some cancer therapy regimens. A European review highlighted continued reports of inadvertent overdose due to more frequent dosing (including daily administration), which has resulted in some fatalities.

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Solifenacin succinate Drugs BNF NICE

(2 days ago) Directions for administrationFor solifenacin succinate. Manufacturer advises for oral suspension, doses should be followed by a glass of water—ingestion with food or other drinks may lead to the release of solifenacin in the mouth, causing a bitter taste and numbness in the mouth.

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Furosemide Drugs BNF NICE

(2 days ago) Resistant oedema. By mouth. Adult. 80–120 mg daily. Initially by intramuscular injection, or by slow intravenous injection, or by intravenous infusion. Adult. Initially 20–50 mg, then (by intramuscular injection or by intravenous injection or by intravenous infusion) increased in steps of 20 mg every 2 hours if required, doses greater than

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Gabapentin Drugs BNF NICE

(1 days ago) Peripheral neuropathic painfor gabapentin. By mouth. Adult. Initially 300 mg once daily on day 1, then 300 mg twice daily on day 2, then 300 mg 3 times a day on day 3, alternatively initially 300 mg 3 times a day on day 1, then increased in steps of 300 mg every 2–3 days in 3 divided doses, adjusted according to response; maximum 3.6 g per day.

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